Asthma & allergy
Leukotriene receptor antagonist
Montelukast
Also known as: Singulair
Best time
Evening
- 19:00–22:00
Taken in the evening for asthma so its peak effect covers the night, when asthma is worst.
Strong evidence
Consistent clinical trials or official prescribing guidance support this timing.
Why this time works
Airway inflammation and narrowing peak around 04:00. Leukotriene levels also rise overnight. Evening montelukast reaches peak levels during this vulnerable window, which is why its label recommends evening dosing for asthma.
Body rhythm involved
Lung function is lowest and airway inflammation highest around 04:00.