Cholesterol
Statin · short half-life
Fluvastatin
Also known as: Lescol, Lescol XL
Best time
Evening (capsules)
- 19:00–23:00
Immediate-release capsules are taken in the evening; the extended-release tablet can be taken any time.
Moderate evidence
Supported by studies and drug pharmacology, but guidance varies between sources.
Why this time works
Fluvastatin capsules are short-acting, so evening dosing better covers night-time cholesterol synthesis. The XL formulation spreads release over the day and is less time-sensitive.
Body rhythm involved
Hepatic cholesterol synthesis peaks overnight.