Cholesterol
Statin · long half-life
Rosuvastatin
Also known as: Crestor
Best time
Any time — keep it consistent
With a ~19-hour half-life, rosuvastatin is effective whether taken in the morning or evening.
Strong evidence
Consistent clinical trials or official prescribing guidance support this timing.
Why this time works
Its long half-life keeps HMG-CoA reductase blocked through the night regardless of dosing time. Trials found no meaningful difference between morning and evening dosing.
Body rhythm involved
Long half-life smooths out the night-time cholesterol peak.