Heart & blood pressure
Thiazide diuretic
Hydrochlorothiazide
Also known as: Microzide, HCTZ
Best time
Morning
- 07:00–10:00
Morning dosing keeps the diuretic effect in the daytime.
Strong evidence
Consistent clinical trials or official prescribing guidance support this timing.
Why this time works
Like other diuretics, hydrochlorothiazide increases urination for several hours. Taking it in the morning reduces sleep disruption from night-time urination.
Body rhythm involved
Urine production normally falls at night.