Brain, mood & sleep
Hypnotic (Z-drug)

Zolpidem

Also known as: Ambien, Stilnox

12:001800:0006

Best time

Immediately before bed

  • 22:00–23:30

Take only when you are getting into bed with 7–8 hours available for sleep.

Strong evidence

Consistent clinical trials or official prescribing guidance support this timing.

Why this time works

Zolpidem acts within ~15–30 minutes. Taking it too early risks sleep-walking or other complex behaviours; taking it with less than 7 hours before waking risks next-morning impairment, especially for driving.

Body rhythm involved

Works with the natural evening rise in sleep pressure.

Other brain, mood & sleep medicines