Medicine library

43 medicines and when they work best in your day.

Type of medicine

Best time of day

18 results

Furosemide

Lasix

Morning (second dose by early afternoon)

Heart & blood pressureStrong evidence

Hydrochlorothiazide

Microzide, HCTZ

Morning

Heart & blood pressureStrong evidence

Isosorbide mononitrate

Imdur, Monoket

Morning & early afternoon (asymmetric)

Heart & blood pressureStrong evidence

Levothyroxine

Synthroid, Euthyrox

On waking, empty stomach — or bedtime

Hormones & diabetesStrong evidence

Prednisolone / prednisone

Deltasone, Pred Forte (oral forms)

Morning

Hormones & diabetesStrong evidence

Hydrocortisone (replacement)

Cortef, Plenadren

Largest dose on waking, smaller early afternoon

Hormones & diabetesStrong evidence

Metformin

Glucophage, Glucophage XR

With meals (XR with the evening meal)

Hormones & diabetesStrong evidence

Glimepiride

Amaryl

With breakfast

Hormones & diabetesStrong evidence

Omeprazole

Prilosec, Losec

30–60 min before breakfast

Stomach & gutStrong evidence

Fluoxetine

Prozac

Morning

Brain, mood & sleepModerate evidence

Methylphenidate

Ritalin, Concerta

Morning (immediate-release also at midday)

Brain, mood & sleepStrong evidence

5-Fluorouracil (chronomodulated)

5-FU infusion

Overnight infusion, peak ~04:00

Cancer therapyEmerging evidence

Oxaliplatin (chronomodulated)

Eloxatin

Daytime infusion, peak ~16:00

Cancer therapyEmerging evidence

Immune checkpoint inhibitors

Pembrolizumab, nivolumab

Morning infusions

Cancer therapyEmerging evidence

Naproxen & other NSAIDs

Aleve, ibuprofen, indomethacin

Depends on the condition

Pain & inflammationModerate evidence

Alendronate

Fosamax

On waking, empty stomach

Bone, kidney & bladderStrong evidence

Tamsulosin

Flomax

30 min after the same meal each day

Bone, kidney & bladderStrong evidence

Influenza vaccine

Seasonal flu shot

Morning appointment

Vaccines & immunityEmerging evidence